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Their use is rising rapidly, and with good reason: These medications have been shown to reduce blood sugar, improve fatty liver, GERD, sleep apnea, osteoarthritis, blood pressure, triglycerides, major adverse cardiovascular events, and even show potential benefits for conditions like alcohol use disorder (Mozaffarian et al., 2025
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Improving the plumbing does not repair the degenerating circuitry. These images show the human hippocampus, a memory-critical region, in Alzheimers disease: H&E (top left): overall structural collapse, neuronal loss, inflammation