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Lipodystrophy manifests as abnormal fat distribution, marked by diminished fat in the face and limbs and increased abdominal and visceral fat, often as a side effect of antiretroviral medication

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This need was recently addressed with the identification of a group of specific peptides that can transport small molecules as well as hydrophilic macromolecules into the cell interior ( This review focuses on the application of nasal delivery of drugs using CPP-based systems based on our current understanding of how CPP can be applied in vivo delivery of peptide drugs through the nasal epithelium and of the potential advantages of the nasal administration route in systemic and brain drug delivery

Shared decision-making ensures that treatment plans align with individual patient circumstances, preferences, and clinical needs, optimising both safety and therapeutic outcomes

Novo Nordisk A/S, Eli Lilly and Company, AstraZeneca plc, Sanofi S.A., Merck & Co., Inc., Boehringer Ingelheim International GmbH and Zealand Pharma A/S are global key players in the market