Trans-differentiation of glioma cells to endothelial cells in vitro was demonstrated by culturing of glioma cancer stem cells in endothelial-promoting media, resulting in expression of pan-endothelial markers CD31, CD34 and vWF, formation of tubular structures and uptake of LDL [59, 77]
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Divide by concentration: 0.25mg 2mg/ml = 0.125ml needed
The mechanism appears to involve both an anti-inflammatory effect on melanocytes and normalization of the barrier function
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