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Most Common Side Effects Can Include: Abdominal pain, increase in heart rate, diarrhea, vomiting, constipation, nausea, headache, fatigue, dyspepsia, dizziness, abdominal distension, eructation, retinal disorder (diabetes mellitus patients), hypoglycemia (diabetes mellitus patients), flatulence, gastroenteritis, lipase increase, gastritis, alopecia, GERD, amylase increase, injection site reaction, hypotension

Some users report a metallic or sulfur-like taste, which is attributed to the cysteine component of the molecule

PMID: 36601368

For patients requiring additional glycemic lowering, the dose can be further up-titrated to 14 mg once daily after taking the 7 mg dose for at least 30 days

We also need trials that measure TMAO and cardiovascular outcomes over many years to be certain about long-term safety in subgroups