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Jennifer Hwang, DO Jennifer Hwang, DO, is a board-certified physician in internal medicine and obesity medicine and provides comprehensive primary care

It also influences various hormones involved in metabolism and energy balance

Safety and effectiveness of longer-term phentermine use: Clinical outcomes from an electronic health record cohort, Obesity (2019) Qsymia, DailyMed (2024) Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial, The Lancet (2011) Long-term drug treatment for obesity: A systematic and clinical review, JAMA (2014) Lillys Zepbound (tirzepatide) superior to Wegovy (semaglutide) in head-to-head trial showing an average weight loss of 20.2% vs

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The most commonly reported effects are gastrointestinal: Nausea (most common, especially early on) Loose stools or diarrhoea Constipation Vomiting Abdominal discomfort or bloating The good news is that these effects are usually mild to moderate, and they tend to settle as your body adapts, typically within the first few weeks of each dose increase