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Common adverse effects predominantly involve the gastrointestinal system and include nausea (reported by 20-44% of patients), diarrhoea, constipation, vomiting, and abdominal discomfort
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More frequent medical oversight than typical clinical care, which some patients value
In short supply since 2022, GLP-1s fit this scenario
Oral semaglutide particularly, has seen commercial success, eg, with sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC)-based Rybelsus
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