Understanding your genetic predispositions in methylation and B12 metabolism can support a more informed conversation with your provider about baseline biomarker testing, appropriate dosing strategy, and expected response timelines
Additionally, a randomized trial showed a benefit in disease-free survival in breast cancer patients receiving presurgical peritumoral injection of lidocaine, which is also a VGSC inhibitor (331)
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In addition, we address sex and gender differences in this bidirectional relationship