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intracellular half-life is prolonged because of lysosomal release and cytosolic resequestration, creating a depot effect that supports monthly maintenance dosing for chronic deficiencies
It acts as an endocrine organ, communicating with the brain, immune system, and metabolism
Cycle timing
Such a step applies in refrigerator settings
However, in our analyses of 13 C-glucose, we found that total and labelled succinate accumulated to higher levels in mutant cells than in Gclc fl/fl FoB (Fig
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