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Meanwhile, GIP receptor activation can also enhance glucose-dependent insulin release through the AKT/PKB signaling pathway and promote -cell proliferation while inhibiting apoptosis, playing an important role in glucose regulation and insulin secretion (Regmi et al., 2024

In univariable analyses, tumor multifocality was significantly negatively correlated with expression of GLP-1R in PTC (odds ratio [OR], 0.257