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-Synuclein has been reported to cause dysfunction of mitochondrial complex I in PD which in turn increases levels of ROS and consequently ROS-induced oxidative stress (Winklhofer and Haass 2010)
Pterostilbene A methylated derivative of resveratrol found in blueberries, pterostilbene has demonstrated superior bioavailability compared to resveratrol and shows BDNF-supporting effects in animal models
This unique mechanism has shown remarkable potential in early human trials for tackling obesity, T2D, and related conditions like non-alcoholic fatty liver disease (NAFLD)
Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron
Images were analyzed with ZEISS ZEN Blue and Fiji softwares
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