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Description

The shared biological properties of exendin-4 and human GLP-1 probably stem from their primary and secondary structures, but exendin-4 is naturally resistant to degradation by the DPP-4 enzyme, attributed to the presence of glycine at position 2, resulting in an intravenous half-life of approximately 30 minutes (85)

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Lpez-Gmez JJ, Prez-Castrilln JL, Garca de Santos I, Prez-Alonso M, Izaola-Jauregui O, Primo-Martn D, et al

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Banerjee R

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Surg Neurol Int 2015;6(suppl 27):S661S667

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For men, the drug can cause priapism a painful erection that does not go away and can damage the penis, requiring emergency treatment

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