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Patients using continuous subcutaneous insulin infusion pump therapy must be trained to administer insulin by injection and have alternate insulin therapy available in case of pump failure [see How Supplied/Storage and Handling (16.2) and Patient Counseling Information (17)]

Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment Of Fertility Standard 2 year carcinogenicity studies in animals have not been performed to evaluate the carcinogenic potential of insulin degludec

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