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J., Varadharajan, V., Hazen, S

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A major trial, the EMPA-REG Outcome study, Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes enrolled patients with type 2 diabetes who were also at high risk of cardiovascular events such as strokes or heart attacks to take Empagliflozin and monitor if there were any beneficial effects in this group

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Clinical evidence: key trials and outcomes GLP-1 receptor agonists have shown kidney benefits in cardiovascular safety trials, primarily by reducing the onset and progression of albuminuria [62]

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Studied primarily in animal models, with limited human clinical data

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