The most common side effects are gastrointestinal: nausea (30-44%), diarrhea (19-30%), constipation (10-24%), and occasional vomiting (9-24%)
In controlled trials, Ipamorelin increased growth hormone without elevating ACTH or cortisol, supporting a smoother profile for consistent progress
Schwille-Kiuntke J, Frick JS, Zanger P, Enck P
GLP-1s may not only help people by reducing alcohol intake, but also protect the liver from alcohol metabolism-mediated damage, says one coauthor of that study, Wajahat Mehal, MD, who directs the Yale Fatty Liver Disease Program and the Yale Metabolic Health and Weight Loss Program in New Haven, Connecticut
Mounjaro (tirzepatide), with its dual GLP-1/GIP action, has shown greater weight reduction (avg