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Heres how that total breaks down: Ozempic: $914.8 million Wegovy: $691.2 million Combined: $1.606 billion Total Medi-Cal Drug Spend in 2024: $16.1 billion This level of spending helped drive the states decision to remove GLP-1s from its covered Medi-Cal formulary in 202526
Much of the early GLP-1 packaging reaction was reactive trend adoption, explained Sean Bisceglia, CEO of packaging design firm WovenWorks (formerly PV&COHO)
Consistent frequency matters more than any single dose optimization
These modifications significantly reduce binding to IGF-binding proteins, resulting in prolonged activity and enhanced receptor interaction in research settings
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