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We could expect from early treatment with oral semaglutide and other GLP-1 analogues a better control of cardiovascular risks as a result of its actions exerted before atherosclerosis develops, in addition to the benefits of superior glucose control and weight loss
As we will probably never have a direct randomized comparison, we have to rely on these inderect comparinos of CV effects of semaglutide and tirzepatide This study combined oral and injectable semaglutide and the comparison with tirzepatide showed no differences in CV outcomes At the same time the efficacy in decreasing body weight and improving metabolic parameters is significantly better for tirzeptide What we dont know yet are CV data for tirzepatide in non-diabetics
The current Nexus record links GHK-CU to finalized batch APX-2026-0313-G.
Lee J, Hong SW, Kim MJ, Kwon H, Park SE, Rhee EJ, et al
doi: 10.1002/iub.1646
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