Final Thoughts Nausea, constipation, and fatigue can happen during GLP-1 therapy, but they should not be ignored when they interfere with hydration, nutrition, muscle preservation, or daily function
Introduction Type 2 diabetes (T2D) is one of the major health concerns affecting 9% of the global population, putting those affected at risk of cardiovascular-associated mortality ( The incretins glucagon-like peptide-1 (GLP-1) and glucose-stimulated insulinotropic polypeptide (GIP) are peptide hormones secreted from intestinal enteroendocrine cells (Nauck and Meier, 2018), with the incretin effect referring to the greater amount of insulin secreted in response to an oral glucose load relative to an equal intravenous dose
As cheaper versions become widely available, adherence and continuity of care could become major concerns
Additionally, the manufacturers Mounjaro Savings Card requires an FDA-approved type 2 diabetes diagnosis, making it difficult for patients to obtain the medication at a reasonable price
Particular emphasis was placed on comprehending the mechanisms of action of these inhibitors and their potential influence on PTC development