Foretinib is a class II inhibitor targeting c-MET, VEGFR2, Recepteurd Origine Nantais (RON), kinase insert domain receptor (KDR), and Fms related tyrosine kinase 1 (Flt-1) with potent inhibition of c-MET kinase activity (enzymatic IC50 1.16 nM) [100]
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J Braz Chem Soc 23(11):20032010 Orian L, Mauri P, Roveri A, Toppo S, Benazzi L, Bosello-Travain V, De Palma A, Maiorino M, Miotto G, Zaccarin M, Polimeno A (2015) Selenocysteine oxidation in glutathione peroxidase catalysis: an MS-supported quantum mechanics study
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10.1111/bcpt.12124 62 LiS.ManyevitchR.SedaliuK.AbdelbakiA.GuptaN.KumarA.et al (2018)