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IGF-1 exerts its biological effect through binding to the IGF1 receptor (IGF1R), its effect is modulated through interaction with a group of binding proteins (IGFBPs), which tend to inhibit the effect of IGF-1 [2]

J Hematol Oncol 13(1):156 Zhao S, Huang M, Yan L, Zhang H, Shi C, Liu J, Zhao S et al (2022a) Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway

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To investigate how CI deficiency affects adipocyte biology, we generated mice lacking the core catalytic subunit of CI, Ndufs2 , specifically within adipocytes 29

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