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Dehydration: If the body is dry, the skin under the eyes will lose the natural glow and look more hollow, thus making the circles more prominent

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Figure 2: Changes in A) percentage of time spent in the red arm, B) percentage of time spent in the start arm, and C) distance swam in mm, between the zebrafish fed a control diet or those fed a HF diet

In contrast, the Cagri-AMY 2 R-Gs complex was stable in the consensus AMYR conformation with stable TM interaction between RAMP2 and CTR, and the peptide maintained a bypass motif