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Ascendis will provide access to its TransCon technology platform in an effort to find GLP-1 candidates with reduced dosing frequency, according to a Monday press release
The potential for increased fertility is a side effect
Mass spectrometry can support identity confirmation, but a matching mass alone does not characterize sequence-related impurities, positional isomers, disulfide variants, aggregates, residual reagents, or all degradation products
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Furthermore, a recent clinical study in women with obesity treated with semaglutide showed improved recognition of basic tastes, altered gene expression in the tongue (measured by tongue biopsy), decreased activation of putamen in response to calorie-dense sweet and savory food cues, and increased cortical brain activity in response to the sweet taste stimulus compared to placebo
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