dupixent and tirzepatide REFILE-FDA approves expanded label for Regeneron/Sanofi's Dupixent (Dupilumab) Approved for Kids

Tirzepatide has been available since 2022, with extensive global clinical experience and FDA approval

Retatrutide is an investigational weight loss drug that produced 28.3% average weight loss in its pivotal Phase 3 trial the highest ever recorded for a single obesity medication

Practically speaking, if you weigh significantly more than the trial average, you may find that: The 2.5 mg initiation dose produces minimal noticeable effect You need to reach higher doses (10-15 mg) before seeing consistent results Your optimal maintenance dose trends toward the upper end of the range Conversely, if you weigh less than the trial average, lower doses may produce significant effects, and the maximum dose may not be necessary or desirable

On average, GoodRx lists the retail price of branded Wegovy in the range of $1,350 to $1,600 for a 28-day supply

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