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Vitamin B12 (cobalamin) is a water-soluble vitamin essential for red blood cell formation, DNA synthesis, and neurological function
And GAS could block the mitogen-activated protein kinases (MAPK) signal pathway, and suppress the inflammatory mediators such as cyclic adenosine monophosphate (cAMP)-response element binding protein (CREB) and nuclear factor kappa-B (NF-B) phosphorylation, in PTZ-treated epileptic mice [35, 36]
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