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Titration to 7.5/46 mg as the standard maintenance dose
It improves fat metabolism, provides additional appetite regulation through central nervous system effects, and appears to reduce GLP-1-related nausea
Furthermore, a decline in glutathione levels can trigger apoptosis signaling, and supplementation with GSH can inhibit this process, exerting a cytoprotective effect
In hemodialysis patients, due to reduced renal clearance, carnitine depletion and acylcarnitine accumulation become significant, resulting in an abnormal increase in the ratio of acylcarnitine to free carnitine in plasma, which in turn inhibits cardiac fatty acid metabolism [261]
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