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Sulfur-rich plasma proteins, including albumin and ceruloplasmin, further buffer redox stress by chelating metal ions and exhibiting thiol-based antioxidant effects (21)
10.1161/01.CIR.0000092184.43176.91 Circulation
In the first normal one, the cells had biophysical and cytological properties, except esterase activity, similar to parameters of cells in control, which were not affected by oxidative stress
Prevalence of Methotrexate Intolerance A quantitative questionnaire based scoring method to determine Methotrexate Intolerance in patients has been developed and termed as MISS (Methotrexate Intolerance Severity Score) [35]
These are based on stability testing and Good Manufacturing Practices (GMP)
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