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Oral semaglutide is taken once daily and reduces HbA 1c levels to a significantly higher extent than DPP-4 inhibition or sodiumglucose cotransporter 2 (SGLT-2) inhibition and to a similar extent as liraglutide, whereas body weight is reduced by a significantly higher extent than by DPP-4 inhibition and liraglutide and to a similar extent as SGLT-2 inhibition [30, 31]

Sergey Terushkin, MD, FACS (954) 551-3508 1911 Harrison Street, Hollywood, FL 33020 Yes

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A heart disease study of semaglutide in patients with type 2 diabetes (SOUL) Accessed 22 Mar 2021

While suggestive of a treatment signal, the result did not reach statistical significance