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Simionescu BC, Drobota M, Timpu D, Vasiliu T, Constantinescu CA, Rebleanu D
S.ChenL
(Glucagon-like peptide 1 (GLP-1): physiology, satiety, and metabolism.) Wilding JPH, et al
Semaglutide and tirzepatide do not directly damage muscle
An invited review in the New England Journal of Medicine stated it plainly: the positive cardiac and renal effects of GLP-1 receptor agonists are more than just improvement in ambient glucose concentrations, pointing to pleiotropic vascular actions as key contributors to the MACE reductions observed across LEADER, SUSTAIN-6, SELECT, and the other landmark trials
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