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Endogenous IGF-1 circulates bound to IGFBP-3 in a ternary complex with the acid-labile subunit, restricting bioavailability to less than 1% of total circulating IGF-1

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Sintetizzata in particolare nel fegato e nei reni , lALCAR svolge un ruolo importante nel metabolismo energetico e facilita il trasporto degli acidi grassi nei mitocondri, dove vengono convertiti in energia

Calculations and statistical analysis For analyses of GLP-1 secretion in perfusion experiments, hormone concentrations are presented in pM as mean values SEM