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(PubMed) Khalili M, Eghtesadi S, Mirshafiey A, et al
In receptor-binding studies, tirzepatide demonstrated a high affinity for the GIPR, comparable to that of native GIP, while its affinity for the GLP-1R is approximately 18- to 20-fold weaker than that of native GLP-1 [33]
Some clients tell me that, after taking a GLP-1, it is the first time *ever* in their life that they experienced the sensation of fullness
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