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The dysregulation of GSH expression strongly correlates with onset and progression of numerous types of disease, including tumors (4), liver disease (5), diabetes (6) and neurodegenerative disease (7,8)
After 48 h, these mice were treated with a daily intraperitoneal injection of JMF4073 for 14 days (Fig
Morris, V
Synthetic pineal tetrapeptide activating hTERT (telomerase reverse transcriptase) expression in somatic cells, reducing oxidative stress markers (MDA, SOD, catalase), and restoring melatonin circadian amplitude in aged models
This early BBB dysfunction and glymphatic system impairment may contribute to the initiation of neurodegenerative processes such as those seen in Alzheimer's disease (Sweeney et al., 2018)
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