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Pharmacological Research, 182 , 106320
107 Interestingly, only an estimated 15% of the active GLP-1 reaches the portal vein before the liver, due to the rapid inactivation through DPP-IV
The hypothalamus can also be hypothesized to regulate satiation or satiety in a feed-forward manner
Other pharma players and biotech companies are knocking on the door -- and if their candidates make it successfully through clinical development and regulatory review, they could make a grand entrance
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