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Each E2p subunit contains two consecutive lipoic acid-bearing domains (LBDs), termed as L1 and L2, one subunit binding domain (SBDp) which binds E1p and the inner-core/catalytic domain containing the E2 p active site responsible for the self assembly of the core which connects with the other independent domains by unstructured linkers [3](Fig.3)

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Zn-DHM nanozymes regulate metabolic and immune homeostasis for early diabetic wound therapy