Clinical Context Asthma in patients with obesity is often characterized by: More severe symptoms Reduced response to inhaled corticosteroids Increased exacerbation frequency Weight loss has been associated with improved asthma control, but pharmacologic options specifically targeting obesity-related asthma are limited
Anti-Inflammatory Action Downregulates pro-inflammatory cytokines (like TNF- and IL-6) while upregulating anti-inflammatory responses
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Frias JP, Davies MJ, Rosenstock J, Perez Manghi FC, Lando F, Bergman L, Liu BK, Cui B, Brown X, K., Investigators S-
This means that restoring estrogen through HRT may actually increase your body natural GLP-1 production, amplifying the effects of exogenous GLP-1 medications