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In addition, more lipophilic drugs will tend to pass not only through the BBB, but also to other organs, which consequently results in a reduced availability of drugs to enter the brain (27)
P.BrandonC
Although the majority of first-time prescriptions occurred in the 45-64 age group, a higher proportion of patients with off-label prescriptions were female (off-label: 69%, on-label: 61%) and between 18-25 (off-label: 30%, on-label: 22%)
The amount of whole-cell GSSG is entirely dependent on Ycf1 and uninformative about the cytosolic glutathione pool
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