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People taking the highest dose of retatrutide lost an average of 24% of their starting body weight thats nearly a quarter of their total weight

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A person who lost 60 pounds and regains 40 after stopping the medication has still lost 20 pounds

Proton pump inhibitors (PPIs) such as omeprazole or pantoprazole may help patients experiencing concurrent reflux symptoms, as delayed gastric emptying can worsen gastroesophageal reflux disease