fda indications for tirzepatide Big update in pediatric diabetes care 🩺 Mounjaro® (tirzepatide) is now FDA- approved children ≥10 years old with Type 2 diabetes as an adjunct to diet and exercise. What this means ⬇️ FDA-Approved Dosages and Indications for

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Only a small, yet significant amount is metabolised via the hepatic cytochrome P450 enzyme system (its CYP2E1 and CYP1A2 isoenzymes), which is responsible for the toxic effects of paracetamol due to a minor alkylating metabolite (N-acetyl-p-benzo-quinone imine, abbreviated as NAPQI).[17] There is a great deal of polymorphism in the P450 gene, and genetic polymorphisms in CYP2D6 have been studied extensively

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While it doesnt act on the vascular system in the same way as PDE5 inhibitors, caution is still advised