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Curcumin has also shown inhibitory effects on the mitochondrial dysfunction in PC12 cells, reducing ROS production and neurotoxicity (R

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Cell Mol Life Sci 57 : 932942 Werner H, Shalita-Chesner M, Abramovitch S, Idelman G, Shaharabani-Gargir L, Glaser T (2000) Regulation of the insulin-like growth factor-I receptor gene by oncogenes and antioncogenes: implications in human cancer