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Recognizing MASLD as a central component of metabolic disease is crucial for preventing its progression to T2DM and enhancing long-term patient outcomes and quality of life

In humans, studies of cardiac surgery patients show a correlation between TLR9 activation (measured by downstream cytokines) and postoperative complications (33)

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The effects of midlife weight gain extend far beyond aesthetics, contributing to an increased risk of heart disease, type 2 diabetes (T2D), and other metabolic diseases