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Nature 380:435439 Henry TD, Annex BH, McKendall GR, Azrin MA, Lopez JJ, Giordano FJ, Shah PK, Willerson JT, Benza RL, Berman DS et al (2003) The VIVA trial: vascular endothelial growth factor in ischemia for vascular angiogenesis
The hydrogen bond network was then optimised and the protein structure minimised to a root mean square deviation of 0.3 with the OPLS4 forcefield [32]