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Gastrointestinal side effects such as diarrhoea are most common during the dose-escalation phase of retatrutide treatment and often improve or resolve once a stable maintenance dose is reached

Lyophilized GHK-Cu should be stored at -20C and protected from light, as the copper complex can undergo photodegradation

The lipid benefits observed with semaglutide appear to be largely mediated through weight reduction, though some direct effects on lipoprotein metabolism may also contribute

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As the deficiency is managed, the frequency can be reduced to weekly and then monthly for upkeep