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In male rats experiencing transient ischemic stroke, UA treatment induced IL-6 expression, upregulated STAT3 and NF-B p65 phosphorylation, induced Socs3 expression, and maintained the ramified morphology of Iba-1-positive microglia in the cerebral cortex, suggesting an anti-inflammatory effect of UA [54]
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Last year, Health Canada added an indication to the label for Ozempic approving it for the treatment of kidney disease in people with diabetes
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