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As in the LEAN study, the primary outcome is histologic resolution of NASH without worsening of fibrosis after 72 weeks of treatment, while secondary outcomes include improvement in liver fibrosis (1 stage) with no worsening of NASH, NAFLD activity score, as well as multiple serum markers of fibrosis
Khan said that, aside from diabetes and weight loss, studies have shown GLP-1s reduce major adverse cardiovascular events, help prevent the onset of diabetes and also improve sleep apnea, arthritis and fatty liver disease outcomes
When appetite decreases significantly, its easy to unintentionally skip meals or fall short on protein intake
Mollan SP, Ali F, Hassan-Smith G, Botfield H, Friedman DI, Sinclair AJ
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