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Such changes may exacerbate autistic behaviors or mood disorders

It is generally well-tolerated, with the following side effects [9][18]: GI symptoms (most common): Nausea, vomiting, diarrhea, and abdominal discomfort, particularly at doses above 1,200 mg/day Sulfurous taste/smell: NAC has a distinct sulfur odor and taste that some find unpleasant Headache: Occasionally reported Anaphylactoid reactions (IV use only): Infusion-related reactions including flushing, itching, bronchospasm, and hypotension occur in approximately 10-20% of patients receiving IV NAC for acetaminophen overdose [18] Upper limit: There is no established UL for NAC

It also makes an excellent choice for people that want to complete a liver detox

Some people also notice an improvement in their overall sense of well-being and a reduction in symptoms associated with deficiency, such as tingling or numbness in the extremities

Depletion of GSH can lead to, among other things, mitochondrial dysfunction and cell death