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PMID 8216285

Disproportionality signals for IGE All five GLP-1RAs had statistically significant reporting odds ratios (RORs) for IGE: Semaglutide: ROR 24.8 Dulaglutide: ROR 14.7 Liraglutide: ROR 13.7 Exenatide: ROR 5.4 Tirzepatide: ROR 18.3 This analysis confirms that these drugs are significantly more likely to be reported in conjunction with IGE compared to other medications

Another observational study from 2024, titled Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide, noted an association between semaglutide, the main drug in Ozempic, and Non - Arteritic Ischemic Optic Neuropathy (NAION), an ocular disease which can cause permanent and severe vision loss