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Mechanism of Action Exogenous GLP-1 RA have been more recently considered as a good choice for treating patients with diabetes it works by incretin effect [1] intestinal component accounts for 50%- 70% of the total insulin secreted after an oral glucose load [2]

Ophthalmology 132 (4), P75p162

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How PlexusDx Supports a More Personalized Approach PlexusDx recognizes that genetic variation in peptide metabolism pathwaysparticularly variants affecting GLP-1 receptor expression, glucose-dependent insulinotropic peptide (GIPR) signaling, and appetite-regulatory genesmay help provide context for why microdosing strategies differ among individuals