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Mol Pharmacol 2001

Dysesthesia associated with GLP-1 agonist therapies: data-mining analysis and literature review

EECs arise from the secretory linage, which also comprises antimicrobial peptide- producing Paneth cells (in the small intestine), Paneth-like cells (in the large intestine), mucin- producing goblet cells, serotonin-producing enterochromaffin cells, and tuft cells involved in chemosensing ( Figure 2B )

* This product may not have the same effect on every person and may affect individual metabolisms differently

They work by blocking the PDE5 enzyme, which helps maintain higher levels of cyclic guanosine monophosphate (cGMP), supporting blood vessel relaxation mediated by nitric oxide