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A wagon of fat symbolized Oprah's willpower but it wasn't enough It was about 37 years ago when talk show host Oprah Winfrey rolled out a red wagon of fat on national TV 67 pounds worth of it from the Chicago-based Moo & Oink meat company to symbolize the weight she'd recently lost

Pistone G, Marino A, Leotta C, et al

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(2024) International Journal of Obesity n=32 fMRI study examining neural responses to food images and appetite-related questionnaires in obese subjects receiving retatrutide versus placebo