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In type 1 diabetes, combination therapies have primarily focused on glucose control and safety, with several randomized controlled trials investigating the effects of combining treatments such as SGLT2is and GLP-1RAs with insulin
Another placebo-controlled trial in older adults at high risk of dementia found that supplementation with vitamin C (200 mg/day) and vitamin E (500 mg/day) for 12 weeks did not alter any of the measured cognitive functions despite nonsignificantly lowering levels of F 2 -isoprostanes biomarkers of lipid peroxidation in vivo (176)
In rats with experimentally induced disc lesions, locally applied BPC-157 increased collagen and blood vessel growth, accelerated healing, and reduced inflammation
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