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While low-level ROS assist host defense by clearing pathogens, sustained overproduction causes oxidative stress that exacerbates tissue damage [407]

So a large oral dose still puts far less into circulation than a smaller injection

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3), which may contribute to the high level of GSH and high GSH/GSSG ratio in the HT+GSH treatment compared to the HT treatment

Since NAD therapy is a newer treatment, its effectiveness is still being studied