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had taken a glucagon-like peptide-1 (GLP-1) receptor agonist medications for the treatment of type 2 diabetes or, increasingly, for weight loss

Fungal invasion typically initiates in the hyponychium, an area of low adhesion of the nail plate, and progresses along the longitudinal ridges of the nail bed, resulting in a linear appearance of the fungal infection.5 In onychoscopy, the most frequent finding is an irregular border pattern with spicules at the proximal margin of the onycholytic area

The peptides that are not growth-hormone secretagogues have a different alcohol problem, but it is still a real problem

These factors indicate that the GLP-1 RA group is more severely affected by diabetes compared to the DPP-4i group, and the GLP-1 RA group may thus be subject to residual confounding associated with higher fracture risk

They do not mean all compounded semaglutide drops are dangerous or ineffective, but they do mean that source quality matters enormously